What is Paratyphoid C?
Paratyphoid C – an acute infectious disease with a fecal-oral mechanism of transmission, similar in pathogenesis and main clinical manifestations to typhoid fever.
Causes of Paratyphoid C
The causative agents of paratyphoid fevers belong to the genus Salmonella, a family of intestinal bacteria. Their morphological and cultural properties are not much different from the causative agent of typhoid fever and other Salmonella groups. They have 8–20 flagella providing their mobility, are optional anaerobes, gram-negative, grow well on ordinary nutrient media, differ from each other in the composition of O- and H-antigens. Paratyphoid B Salmonella may have an M-antigen, which belongs to the group of surface K-antigens, as well as a Vi-antigen that is different from that of typhoid bacteria. Salmonella paratyphoid C, belongs to the C1 group (O-antigens – VI, VII).
Pathogenesis during Paratyphoid C
Paratyphoid C, occurring in the form of food toxicoinfection and in other forms (rarely occurs, mainly in persons weakened by another infection or chronic disease. Paratyphoid pathogens are excreted in feces and urine; they are stable in the external environment (they survive in milk at 18–20 ° C for up to 10 days, in soil for several months. Transmission factors are water, food, flies, and infected objects.
The nature of the morphological changes in the intestines that occur when paratyphoid Salmonella infection, differs from that of typhoid fever. The minimum infectious dose for paratyphoid fever is ten times higher than for typhoid fever.