Klebsiella in Children

What is Klebsiella in Children?

Klebsiella infection is also known as Klebsiella or Klebsiella (by the name of the pathogen) – a group of infectious diseases that are caused by opportunistic microorganisms that are common in newborns and young children.

An infected adult / child or a healthy carrier of the infection spreads the infection. The main route of transmission is fecal-oral. Such paths as contact and airborne are also possible. From patients, along with secretions, the causative agent of the disease enters the external environment. They maintain their vital activity at room and low temperatures. In the refrigerator, Klebsiella do not die. It is also difficult to kill them with disinfectant solutions and most antibiotics.

Klebsiella often cause nosocomial outbreaks. In children, the disease mainly excites K. pneumoniae. Newborns and infants are very sensitive to it. Contribute to the development of the disease, malnutrition and congenital heart defects, prematurity, acute respiratory viral infections, immunodeficiency states. Klebsiella cause group and sporadic incidence, approximately equal in all seasons.

Causes of Klebsiella in Children

Klebsiella are gram-negative fixed capsule rods. Their size is 0.3-1.5×0.6-6 microns. They are located singly, in pairs or grouped in short chains. On nutrient media at a temperature of 35–37 ˚С, Klebsiella growth is observed, which form mucous shiny colonies similar to domes.

Processing with bactericidal soap often does not kill the causative agent of Klebsiella infection. The same goes for disinfectants.

The disease in humans is excited by three types of Klebsiella: K. pneumoniae, K. rhino-scleromatis and K. ozaenae.

Pathogenesis during Klebsiella in Children

Some strains of K. pneumoniae produce a fairly strong enterotoxin, which causes severe morphological changes in various organs and systems. This enterotoxin leads to disseminated intravascular coagulation.

At the same time, in the area of ​​primary foci, immune complexes are rapidly formed that have a pathogenic effect on tissues. Enterotoxin leads to hemodynamic disturbances in the lesions: in bronchial tissue, in the intestinal wall. In the lungs, under the influence of enterotoxin, the decomposition of surfactant occurs and the formation of atelectasis.